নির্দেশনা

Fluconazole eye drop is indicated in the treatment of fungal corneal ulcers/ keratitis.

Composition

ফার্মাকোলজি

Fluconazole eye drop is a topical ophthalmic solution containing Fluconazole (a bis-triazole derivative) having established therapeutic activity against superficial ocular fungal infections. Fluconazole is fungistatic in action. The drug inhibits cytochrome P-450 14-alfa demethylase in susceptible fungi which leads to alteration of cellular membrane resulting in increased membrane permeability, leakage of essential elements and impaired uptake of precursor molecules to DNA.

মাত্রা ও সেবনবিধি

Instill 1 drop to be instilled into the affected eye(s) 5 times daily.

প্রতিনির্দেশনা

The drug is contraindicated in patients with hypersensitivity to azoles.

পার্শ্ব প্রতিক্রিয়া

This drug is generally well tolerated. Eosinophillia has been reported in some patients.

গর্ভাবস্থায় ও স্তন্যদানকালে

There are no adequate and well-controlled studies in pregnant women. Fluconazole should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Nursing mother should not be given as the drug is excreted in breast milk in concentration similar to plasma.

সতর্কতা

Use of fluconazole may result in overgrowth of non-susceptible strains of candida other than Candida albicans

থেরাপিউটিক ক্লাস

Ophthalmic Anti-fungal Products

সংরক্ষণ