Indications

Cyclizine Hydrochloride is indicated in- Motion sickness: Cyclizine Hydrochloride is indicated for the prevention and treatment of nausea and vomiting. PONV (Postoperative nausea & vomiting) Meniere's disease etc.

Composition

Pharmacology

Cyclizine Hydrochloride is an US FDA approved antihistaminic antiemetic drug. It possesses anticholinergic and antiemetic properties. It reduces excitability of inner ear labyrinth and acts directly on vomiting (Emetic) centre in the brain stem.

Dosage & Administration

Motion Sickness: Adults : 1 Tablet (50 mg) Children: (6 years & above) : 1/2 Tablet (25 mg). 1 tablet should be taken at least 30 minutes before journey (before or after meal), repeat 1 tablet if journey is more than 6 hours Postoperative Nausea & Vomiting, Meniere's disease: Adults : 1 Tablet (50 mg) every 6-8 hours daily Children: (6 years & above) : 1/2 Tablet (25 mg) every 6-8 hours daily

Contraindications

Hypersensitivity to the active substance or to the other excipients. Cyclizine is contraindicated in the presence of acute alcohol intoxication. The anti-emetic properties of cyclizine may increase the toxicity of alcohol.

Side Effects

Itching or skin rashes, swelling of the face, lips or throat, difficulty in breathing or wheeziness.

Pregnancy & Lactation

It is safe in pregnancy according to TGA category "A" & US FDA category "B". Cyclizine Hydrochloride is excreted in milk. So in case of lactating mother, precaution should be taken before taking Cyclizine Hydrochloride.

Precautions & Warnings

Cyclizine Hydrochloride should be used with caution and appropriate monitoring in patients with glaucoma, urinary retention, obstructive disease of the gastrointestinal tract, hepatic disease, hypertension, epilepsy, severe heart failure.

Therapeutic Class

Anti-emetic drugs

Storage Conditions

Store below 30°C temperature.Protected from light & moisture.Keep all the medicines out of the reach of children.