Indications

This is indicated in onychomycosis caused by dermatophytes, yeasts and moulds.

Composition

Pharmacology

Amorolfine is a topical antimycotic. It belongs to a new chemical class of Morpholine, Its fungistatic or fungicidal effect is based on an alteration of the fungal cell membrane targeted primarily on sterol biosynthesis. Amorolfine has a broad spectrum of action. Amorolfine is effective against Yeasts. Dermatophytes. Moulds, Dematiaceae and Dimorphic Fungi.

Dosage & Administration

Amorolfine Nail Lacquer should be applied to the affected finger or toenails once or twice a week as directed by the doctor It is important to use Amorolfine until the infection has cleared and healthy nails have grown back usually takes 6 months for fingernails and 9 to 12 months for toenails.

Contraindications

Must not be reused by patients who have shown hypersensitivity to the treatment.

Side Effects

Rare side-effects (occurring in less than 1 in 1000 people)- Nail may become discolored broken or brittle. Very rare side-effects (occurring in less than 1 in 10000 people)- A burning sensation or allergic skin reaction (contact dermatitis) Unknown frequency of occurrence-Skin redness, itching hives, blisters and allergic skin reaction (contact dermatitis).

Pregnancy & Lactation

No data available on the use of Amorolfine in pregnant women. There is no information on whether Amorolfine passes into human breast milk. There are no data on the use of Amorolfine in lactating women.

Precautions & Warnings

Avoid the lacquer coming into contact with the eyes, ears or mucous membranes (eg. mouth and nostrils). Do not inhale Wear impermeable gloves when using organic solvents to stop the ball lacquer from being removed.

Therapeutic Class

Other preparations

Storage Conditions

Do not store above 30°C. Protect Clinell lacquer from heat. Keep the bottle tightly closed.