Indications

Ascon-F is indicated for the treatment of asthma and COPD. Asthma : This inhaler is indicated in the regular treatment of asthma where use of a combination of inhaled corticosteroid and long-acting P2 adrenergic agonist is appropriate. COPD : This inhaler is indicated for the symptomatic treatment of severe COPD and a history of repeated exacerbations despite regular therapy with long acting bronchodilators.

Composition

Pharmacology

This preparation is a combination of Beclomethasone Dipropionate BP and Formoterol Fumarate Dihydrate BP. It is a hydrofluoroalkane (HFA) based environment friendly inhaler. Because it does not contain chlorofluorocarbon (CFC) as propellant which is one of the main reasons of ozone layer depletion. Beclomethasone Dipropionate is a synthetic halogenated corticosteroid with potent anti-inflammatory activity. It given by inhalation has a potent glucocorticoid anti-inflammatory action within the lungs without the side effects observed when steroids are administered systemically. Formoterol Fumarate Dihydrate is a long acting selective P2 adrenergic agonist with a rapid onset of action. Inhaled Formoterol acts in the lung as a bronchodilator.When used as an inhaler, the medication goes directly into the lungs and very little finds its way into the rest of the body.

Dosage & Administration

Asthma : Dosage should be adjusted according to disease severity. When control has been achieved, the dose should be titrated to the lowest effective dose. Maintenance Therapy : Adults & Adolescents (18 years & above): One or two inhalations twice daily.The maximum daily dose is 4 inhalations. Maintenance and reliever therapy : Patients take a daily maintenance dose of this inhaler as needed in response to symptoms. Patients should be advised to always have this inhaler available for rescue use. Adults & Adolescents (18 years & above) : One inhalation twice daily. If symptoms persist after a few minutes, an additional inhalation should be taken. The maximum daily dose is 8 inhalations. COPD : 2 Inhalations twice daily.

Contraindications

Beclomethasone Dipropionate BP and Formoterol Fumarate Dihydrate BP HFA Inhaler is contraindicated in patients with hypersensitivity to any of the constituents.

Side Effects

Common side effects : Adverse events which have been associated with Beclomethasone and Formoterol are hypokalemia, headache, tremor, palpitations, cough, muscle spasms and prolongation of QTs interval. Rear Side Effects : Rash, Urticaria pruritus, erhythema and oedema of the eyes, face,lips & throat may also occur.

Pregnancy & Lactation

Administration of this inhaler in pregnant women and lactating mother should only be considered if the expected benefit to the mother is greater than any possible risk to the fetus.

Precautions & Warnings

Treatment with Beclomethasone and Formoterol combination should not be initiated to treat a severe exacerbation or if patients have significantly worsening or acutely deteriorating asthma.

Therapeutic Class

Respiratory corticosteroids

Storage Conditions

Do not puncture, break or incinerate the pressurized canister even when apparently empty. Avoid storage in direct sunlight and heat. Store below 30° C temperature & dry place, protected from light. Keep away from children. Keep away from eyes.